Iron Supplement Classification

Iron TypeFormChelated?Elemental Iron %BioavailabilityGI ToleranceCommon Uses / Notes
Ferrous SulfateInorganic Salt❌ No~20%ModerateModerate–LowMost prescribed globally; may cause constipation/gastric distress
Ferrous FumarateInorganic Salt❌ No~33%Moderate–HighModerateHigh elemental iron; often used in pregnancy
Ferrous GluconateInorganic Salt❌ No~12%ModerateGoodGentler on stomach; used in pediatric/geriatric formulations
Iron BisglycinateAmino Acid Chelate✅ Yes~20%HighVery GoodSuperior absorption and GI tolerance; ideal for sensitive users
Iron GlycinateAmino Acid Chelate✅ Yes~20%HighExcellentSimilar to bisglycinate; often used in multivitamin blends
Iron AspartateAmino Acid Chelate✅ Yes~18–20%Moderate–HighGoodLess common; niche premium formulations
Iron OrotateMineral Chelate✅ Yes~15–20%Moderate–HighGoodMarketed as high cell penetration iron; premium but less studied
Iron Polysaccharide ComplexComplexed Iron⚠️ Semi-Chelated~100%ModerateVery GoodNon-ionic; gentle release; useful for long-term supplementation
Carbonyl IronElemental Iron❌ No~100%Slow-releaseVery GoodMicro-pure iron particles; safer for children; low reactivity
Heme Iron PolypeptideOrganic (Animal-Based)✅ Yes~11%Very HighExcellentFrom bovine hemoglobin; ideal for meat-deficient individuals
Ferric CitrateInorganic (Ferric)❌ No~18%ModerateModerateUsed in CKD to manage phosphate and iron simultaneously